COMT Stable Expression Cell Line (THP-1)

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  • 细胞图0 COMT Stable Expression Cell Line (THP-1)-细胞图0
  • 细胞图1 COMT Stable Expression Cell Line (THP-1)-细胞图1
  • 质粒图0 COMT Stable Expression Cell Line (THP-1)-质粒图0
  • COMT Stable Expression Cell Line (THP-1) COMT Stable Expression Cell Line (THP-1)-产品图
细胞图0 COMT Stable Expression Cell Line (THP-1)-细胞图0
细胞图1 COMT Stable Expression Cell Line (THP-1)-细胞图1
质粒图0 COMT Stable Expression Cell Line (THP-1)-质粒图0
COMT Stable Expression Cell Line (THP-1) COMT Stable Expression Cell Line (THP-1)-产品图
COMT Stable Expression Cell Line (THP-1) Copy Product Info
Catalog#： YOE-L098
Size： 1*10^6
Culture method： 90%RPMI-1640+10%FBS
STR Report
Datasheet (Use Instruction)
  • 细胞图0 COMT Stable Expression Cell Line (THP-1)-细胞图0
  • 细胞图1 COMT Stable Expression Cell Line (THP-1)-细胞图1
  • 质粒图0 COMT Stable Expression Cell Line (THP-1)-质粒图0
  • COMT Stable Expression Cell Line (THP-1) COMT Stable Expression Cell Line (THP-1)-产品图
COMT Stable Expression Cell Line (THP-1) Copy Product Info
Catalog#： YOE-L098
Size： 1*10^6
Culture method： 90%RPMI-1640+10%FBS
Datasheet (Use Instruction)

Detailed Product Information

Cell Info

Catalog YOE-L098 Transcript NM_000754.4
Cell name COMT Stable Expression Cell Line (THP-1) Species Human
Gene Name COMT Passage ratio 1：2-1：4
Cell Morphology Monocyte,suspension Antibiotic Concentration Puro=2μg/ml
Culture method 90%RPMI-1640+10%FBS Mycoplasma test negative
Catalog
YOE-L098
Cell name
COMT Stable Expression Cell Line (THP-1)
Gene Name
COMT
Cell Morphology
Monocyte,suspension
Passage ratio
1：2-1：4
Transcript
NM_000754.4
Species
Human
Antibiotic Concentration
Puro=2μg/ml
Mycoplasma test
negative
Culture method
90%RPMI-1640+10%FBS

Product Description

Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters.
Gene Expression Validation
No. Sample hCOMT-1CтMean β-h_actinCтMean ΔCтMean ΔΔCт Expression Rate
1 COMT Stable Expression Cell Line (THP-1) 16.663 14.4 2.263 -2.045 4.127
2 THP-1_Ctrl(Puro) 18.142 13.834 4.308 0.000 1.000
STR Profile
Download STR Report
Loci STR Info (Sample Cell)
Sample Cell Line:THP-1		 STR Info (Cell bank)
Cell Line:THP-1
Allele1Allele2Allele3Allele1Allele2Allele3
D5S818 11121112
D13S317 13131313
D7S820 10101010
D16S539 11121112
VWA 16161616
TH01 89.389.3
AMEL XYXY
TPOX 811811
CSF1PO 11131113
D12S391 1919
FGA 2425
D2S1338 1718
D21S11 3031.2
D18S51 1314
D8S1179 1014
D3S1358 1517
D6S1043 1414
PENTAE 1115
D19S433 12.213
PENTAD 1012
D1S1656 1617
* STR authentication data of this cell line matches with that of cell lines sourced from ATCC, DSMZ, JCRB, and RIKEN databases.
Conclusion: The STR identification of this cell is correct.

Product Advantage

  • icon
    High expression
    Exclusive cell selection technique, ensuing high expression, RT-qPCR validation data provided.
  • icon
    Good stability
    Stable gene copy number, low passage, can be stably passaged for more than 20 passages.
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    Strict QC
    Strict quality control, ensuing no bacterial and mycoplasma contamination, STR authentication and cell post-thawing viability test passed; High standard delivery.
Citations:
Product Catalog#：YOE-L098
Product Name：COMT Stable Expression Cell Line (THP-1)
Related Resources: Red Cotton Gene-editing System | ATCC | DSMZ | ECAZZ | Cellosaurus | CCTCC | NCBI
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